Qualification: 25 runs
| 139.62 (74/53) | HH Gibbs | South Africa v India at Nagpur, 5th ODI, 19/03/2000 [1576] |
| 129.31 (75/58) | L Klusener | South Africa v India at Nagpur, 5th ODI, 19/03/2000 [1576] |
| 123.33 (37/30) | JH Kallis | South Africa v India at Kochi, 1st ODI, 09/03/2000 [1572] |
| 122.58 (38/31) | WJ Cronje | South Africa v India at Nagpur, 5th ODI, 19/03/2000 [1576] |
| 119.35 (37/31) | HH Gibbs | South Africa v India at Vadodara, 4th ODI, 17/03/2000 [1575] |
| 112.85 (79/70) | R Dravid | India v South Africa at Nagpur, 5th ODI, 19/03/2000 [1576] |
| 110.71 (31/28) | SC Ganguly | India v South Africa at Kochi, 1st ODI, 09/03/2000 [1572] |
| 104.49 (93/89) | SR Tendulkar | India v South Africa at Nagpur, 5th ODI, 19/03/2000 [1576] |
| 104.00 (26/25) | SR Tendulkar | India v South Africa at Kochi, 1st ODI, 09/03/2000 [1572] |
| 103.70 (56/54) | SC Ganguly | India v South Africa at Faridabad, 3rd ODI, 15/03/2000 [1574] |
| 103.57 (87/84) | SC Ganguly | India v South Africa at Vadodara, 4th ODI, 17/03/2000 [1575] |
| 97.67 (42/43) | RR Singh | India v South Africa at Kochi, 1st ODI, 09/03/2000 [1572] |
| 96.42 (27/28) | HH Gibbs | South Africa v India at Jamshedpur, 2nd ODI, 12/03/2000 [1573] |
| 96.29 (26/27) | WJ Cronje | South Africa v India at Vadodara, 4th ODI, 17/03/2000 [1575] |
| 93.49 (115/123) | G Kirsten | South Africa v India at Kochi, 1st ODI, 09/03/2000 [1572] |
| 93.10 (27/29) | DM Benkenstein | South Africa v India at Vadodara, 4th ODI, 17/03/2000 [1575] |
| 92.95 (66/71) | WJ Cronje | South Africa v India at Faridabad, 3rd ODI, 15/03/2000 [1574] |
| 88.40 (122/138) | SR Tendulkar | India v South Africa at Vadodara, 4th ODI, 17/03/2000 [1575] |
| 87.40 (111/127) | HH Gibbs | South Africa v India at Kochi, 1st ODI, 09/03/2000 [1572] |
| 84.40 (92/109) | A Jadeja | India v South Africa at Kochi, 1st ODI, 09/03/2000 [1572] |
| 83.78 (93/111) | G Kirsten | South Africa v India at Faridabad, 3rd ODI, 15/03/2000 [1574] |
| 82.85 (29/35) | RR Singh | India v South Africa at Nagpur, 5th ODI, 19/03/2000 [1576] |
| 82.55 (71/86) | WJ Cronje | South Africa v India at Jamshedpur, 2nd ODI, 12/03/2000 [1573] |
| 82.35 (42/51) | M Azharuddin | India v South Africa at Kochi, 1st ODI, 09/03/2000 [1572] |
| 79.59 (39/49) | M Azharuddin | India v South Africa at Vadodara, 4th ODI, 17/03/2000 [1575] |
| 78.26 (72/92) | G Kirsten | South Africa v India at Vadodara, 4th ODI, 17/03/2000 [1575] |
| 76.41 (81/106) | JH Kallis | South Africa v India at Vadodara, 4th ODI, 17/03/2000 [1575] |
| 75.53 (105/139) | SC Ganguly | India v South Africa at Jamshedpur, 2nd ODI, 12/03/2000 [1573] |
| 73.91 (68/92) | MV Boucher | South Africa v India at Nagpur, 5th ODI, 19/03/2000 [1576] |
| 66.97 (73/109) | R Dravid | India v South Africa at Faridabad, 3rd ODI, 15/03/2000 [1574] |
| 64.44 (29/45) | M Azharuddin | India v South Africa at Jamshedpur, 2nd ODI, 12/03/2000 [1573] |
| 63.63 (28/44) | N Boje | South Africa v India at Jamshedpur, 2nd ODI, 12/03/2000 [1573] |
| 61.01 (36/59) | R Dravid | India v South Africa at Jamshedpur, 2nd ODI, 12/03/2000 [1573] |
| 55.35 (31/56) | A Jadeja | India v South Africa at Faridabad, 3rd ODI, 15/03/2000 [1574] |