| 84 | A Flintoff | England v Pakistan at Karachi, 1st ODI, 24/10/2000 [1645] |
| 75* | Abdur Razzaq | Pakistan v England at Karachi, 1st ODI, 24/10/2000 [1645] |
| 73 | N Hussain | England v Pakistan at Karachi, 1st ODI, 24/10/2000 [1645] |
| 71 | Inzamam-ul-Haq | Pakistan v England at Karachi, 1st ODI, 24/10/2000 [1645] |
| 65 | ME Trescothick | England v Pakistan at Lahore, 2nd ODI, 27/10/2000 [1649] |
| 64* | GP Thorpe | England v Pakistan at Karachi, 1st ODI, 24/10/2000 [1645] |
| 61 | Shahid Afridi | Pakistan v England at Lahore, 2nd ODI, 27/10/2000 [1649] |
| 60* | Inzamam-ul-Haq | Pakistan v England at Rawalpindi, 3rd ODI, 30/10/2000 [1653] |
| 58* | Saleem Elahi | Pakistan v England at Lahore, 2nd ODI, 27/10/2000 [1649] |
| 56 | GA Hick | England v Pakistan at Karachi, 1st ODI, 24/10/2000 [1645] |
| 54 | N Hussain | England v Pakistan at Lahore, 2nd ODI, 27/10/2000 [1649] |
| 41 | Saeed Anwar | Pakistan v England at Lahore, 2nd ODI, 27/10/2000 [1649] |
| 39* | Yousuf Youhana | Pakistan v England at Lahore, 2nd ODI, 27/10/2000 [1649] |
| 39 | GP Thorpe | England v Pakistan at Rawalpindi, 3rd ODI, 30/10/2000 [1653] |
| 36 | ME Trescothick | England v Pakistan at Rawalpindi, 3rd ODI, 30/10/2000 [1653] |
| 35 | Yousuf Youhana | Pakistan v England at Karachi, 1st ODI, 24/10/2000 [1645] |
| 31 | Yousuf Youhana | Pakistan v England at Rawalpindi, 3rd ODI, 30/10/2000 [1653] |
| 30 | Imran Nazir | Pakistan v England at Karachi, 1st ODI, 24/10/2000 [1645] |
| 28 | Saleem Elahi | Pakistan v England at Karachi, 1st ODI, 24/10/2000 [1645] |
| 24 | Saeed Anwar | Pakistan v England at Karachi, 1st ODI, 24/10/2000 [1645] |
| 23 | MA Ealham | England v Pakistan at Rawalpindi, 3rd ODI, 30/10/2000 [1653] |
| 23 | Saleem Elahi | Pakistan v England at Rawalpindi, 3rd ODI, 30/10/2000 [1653] |
| 22 | AJ Stewart | England v Pakistan at Lahore, 2nd ODI, 27/10/2000 [1649] |
| 20 | GP Thorpe | England v Pakistan at Lahore, 2nd ODI, 27/10/2000 [1649] |
