| 100.00 (29/29) | FA Rose | West Indies v England at Lord's, 2nd Test, 29/06/2000 [1503] |
| 96.29 (26/27) | DG Cork | England v West Indies at The Oval, 5th Test, 31/08/2000 [1509] |
| 88.88 (48/54) | FA Rose | West Indies v England at Birmingham, 1st Test, 15/06/2000 [1500] |
| 87.09 (27/31) | RR Sarwan | West Indies v England at The Oval, 5th Test, 31/08/2000 [1509] |
| 80.00 (36/45) | CEL Ambrose | West Indies v England at Manchester, 3rd Test, 03/08/2000 [1506] |
| 77.77 (28/36) | CEL Ambrose | West Indies v England at The Oval, 5th Test, 31/08/2000 [1509] |
| 75.75 (25/33) | GA Hick | England v West Indies at Lord's, 2nd Test, 29/06/2000 [1503] |
| 71.95 (59/82) | RR Sarwan | West Indies v England at Leeds, 4th Test, 17/08/2000 [1508] |
| 70.88 (112/158) | BC Lara | West Indies v England at Manchester, 3rd Test, 03/08/2000 [1506] |
| 68.62 (105/153) | AJ Stewart | England v West Indies at Manchester, 3rd Test, 03/08/2000 [1506] |
| 67.34 (33/49) | DG Cork | England v West Indies at Lord's, 2nd Test, 29/06/2000 [1503] |
| 63.04 (29/46) | NAM McLean | West Indies v England at The Oval, 5th Test, 31/08/2000 [1509] |
| 62.10 (59/95) | GA Hick | England v West Indies at Leeds, 4th Test, 17/08/2000 [1508] |
| 61.40 (35/57) | RD Jacobs | West Indies v England at Leeds, 4th Test, 17/08/2000 [1508] |
| 61.36 (27/44) | RDB Croft | England v West Indies at Manchester, 3rd Test, 03/08/2000 [1506] |
| 61.34 (73/119) | S Chanderpaul | West Indies v England at Birmingham, 1st Test, 15/06/2000 [1500] |
| 57.57 (76/132) | MP Vaughan | England v West Indies at Leeds, 4th Test, 17/08/2000 [1508] |
| 57.14 (28/49) | SL Campbell | West Indies v England at The Oval, 5th Test, 31/08/2000 [1509] |
| 54.45 (55/101) | SL Campbell | West Indies v England at Manchester, 3rd Test, 03/08/2000 [1506] |
| 53.76 (50/93) | BC Lara | West Indies v England at Birmingham, 1st Test, 15/06/2000 [1500] |
| 52.90 (82/155) | SL Campbell | West Indies v England at Lord's, 2nd Test, 29/06/2000 [1503] |
| 49.16 (59/120) | SL Campbell | West Indies v England at Birmingham, 1st Test, 15/06/2000 [1500] |
| 49.16 (59/120) | WW Hinds | West Indies v England at Lord's, 2nd Test, 29/06/2000 [1503] |
| 46.42 (26/56) | NV Knight | England v West Indies at Birmingham, 1st Test, 15/06/2000 [1500] |
| 45.76 (27/59) | C White | England v West Indies at Lord's, 2nd Test, 29/06/2000 [1503] |
| 45.19 (47/104) | BC Lara | West Indies v England at The Oval, 5th Test, 31/08/2000 [1509] |
| 44.66 (46/103) | GP Thorpe | England v West Indies at Leeds, 4th Test, 17/08/2000 [1508] |
| 44.44 (28/63) | MA Atherton | England v West Indies at Manchester, 3rd Test, 03/08/2000 [1506] |
| 44.08 (41/93) | MP Vaughan | England v West Indies at Lord's, 2nd Test, 29/06/2000 [1503] |
| 43.10 (25/58) | WW Hinds | West Indies v England at Manchester, 3rd Test, 03/08/2000 [1506] |
| 42.62 (26/61) | RD Jacobs | West Indies v England at The Oval, 5th Test, 31/08/2000 [1509] |
| 41.17 (28/68) | AJ Stewart | England v West Indies at Lord's, 2nd Test, 29/06/2000 [1503] |
| 40.62 (78/192) | ME Trescothick | England v West Indies at The Oval, 5th Test, 31/08/2000 [1509] |
| 40.49 (66/163) | ME Trescothick | England v West Indies at Manchester, 3rd Test, 03/08/2000 [1506] |
| 38.78 (83/214) | MA Atherton | England v West Indies at The Oval, 5th Test, 31/08/2000 [1509] |
| 37.83 (42/111) | RD Jacobs | West Indies v England at Manchester, 3rd Test, 03/08/2000 [1506] |
| 37.62 (38/101) | ME Trescothick | England v West Indies at Manchester, 3rd Test, 03/08/2000 [1506] |
| 37.14 (26/70) | WW Hinds | West Indies v England at Manchester, 3rd Test, 03/08/2000 [1506] |
| 36.00 (36/100) | RR Sarwan | West Indies v England at Manchester, 3rd Test, 03/08/2000 [1506] |
| 33.00 (34/103) | NV Knight | England v West Indies at Birmingham, 1st Test, 15/06/2000 [1500] |
| 32.77 (98/299) | JC Adams | West Indies v England at Birmingham, 1st Test, 15/06/2000 [1500] |
| 32.62 (108/331) | MA Atherton | England v West Indies at The Oval, 5th Test, 31/08/2000 [1509] |
| 31.46 (45/143) | MA Atherton | England v West Indies at Lord's, 2nd Test, 29/06/2000 [1503] |
| 29.67 (27/91) | AFG Griffith | West Indies v England at Lord's, 2nd Test, 29/06/2000 [1503] |
| 29.00 (29/100) | MP Vaughan | England v West Indies at Manchester, 3rd Test, 03/08/2000 [1506] |
| 27.55 (54/196) | AFG Griffith | West Indies v England at Manchester, 3rd Test, 03/08/2000 [1506] |
| 25.31 (40/158) | GP Thorpe | England v West Indies at The Oval, 5th Test, 31/08/2000 [1509] |
| 24.65 (53/215) | JC Adams | West Indies v England at Manchester, 3rd Test, 03/08/2000 [1506] |
| 24.03 (25/104) | AJ Stewart | England v West Indies at The Oval, 5th Test, 31/08/2000 [1509] |