| 112 | BC Lara | West Indies v England at Manchester, 3rd Test, 03/08/2000 [1506] |
| 108 | MA Atherton | England v West Indies at The Oval, 5th Test, 31/08/2000 [1509] |
| 105 | AJ Stewart | England v West Indies at Manchester, 3rd Test, 03/08/2000 [1506] |
| 98 | JC Adams | West Indies v England at Birmingham, 1st Test, 15/06/2000 [1500] |
| 83 | MA Atherton | England v West Indies at The Oval, 5th Test, 31/08/2000 [1509] |
| 82 | SL Campbell | West Indies v England at Lord's, 2nd Test, 29/06/2000 [1503] |
| 78 | ME Trescothick | England v West Indies at The Oval, 5th Test, 31/08/2000 [1509] |
| 76 | MP Vaughan | England v West Indies at Leeds, 4th Test, 17/08/2000 [1508] |
| 73 | S Chanderpaul | West Indies v England at Birmingham, 1st Test, 15/06/2000 [1500] |
| 66 | ME Trescothick | England v West Indies at Manchester, 3rd Test, 03/08/2000 [1506] |
| 59* | RR Sarwan | West Indies v England at Leeds, 4th Test, 17/08/2000 [1508] |
| 59 | SL Campbell | West Indies v England at Birmingham, 1st Test, 15/06/2000 [1500] |
| 59 | WW Hinds | West Indies v England at Lord's, 2nd Test, 29/06/2000 [1503] |
| 59 | GA Hick | England v West Indies at Leeds, 4th Test, 17/08/2000 [1508] |
| 55 | SL Campbell | West Indies v England at Manchester, 3rd Test, 03/08/2000 [1506] |
| 54 | AFG Griffith | West Indies v England at Manchester, 3rd Test, 03/08/2000 [1506] |
| 53 | JC Adams | West Indies v England at Manchester, 3rd Test, 03/08/2000 [1506] |
| 50 | BC Lara | West Indies v England at Birmingham, 1st Test, 15/06/2000 [1500] |
| 48 | FA Rose | West Indies v England at Birmingham, 1st Test, 15/06/2000 [1500] |
| 47 | BC Lara | West Indies v England at The Oval, 5th Test, 31/08/2000 [1509] |
| 46 | GP Thorpe | England v West Indies at Leeds, 4th Test, 17/08/2000 [1508] |
| 45 | MA Atherton | England v West Indies at Lord's, 2nd Test, 29/06/2000 [1503] |
| 42* | RD Jacobs | West Indies v England at Manchester, 3rd Test, 03/08/2000 [1506] |
| 41 | MP Vaughan | England v West Indies at Lord's, 2nd Test, 29/06/2000 [1503] |
| 40 | GP Thorpe | England v West Indies at The Oval, 5th Test, 31/08/2000 [1509] |
| 38* | ME Trescothick | England v West Indies at Manchester, 3rd Test, 03/08/2000 [1506] |
| 36* | CEL Ambrose | West Indies v England at Manchester, 3rd Test, 03/08/2000 [1506] |
| 36 | RR Sarwan | West Indies v England at Manchester, 3rd Test, 03/08/2000 [1506] |
| 35 | RD Jacobs | West Indies v England at Leeds, 4th Test, 17/08/2000 [1508] |
| 34 | NV Knight | England v West Indies at Birmingham, 1st Test, 15/06/2000 [1500] |
| 33* | DG Cork | England v West Indies at Lord's, 2nd Test, 29/06/2000 [1503] |
| 29 | FA Rose | West Indies v England at Lord's, 2nd Test, 29/06/2000 [1503] |
| 29 | MP Vaughan | England v West Indies at Manchester, 3rd Test, 03/08/2000 [1506] |
| 29 | NAM McLean | West Indies v England at The Oval, 5th Test, 31/08/2000 [1509] |
| 28 | AJ Stewart | England v West Indies at Lord's, 2nd Test, 29/06/2000 [1503] |
| 28 | MA Atherton | England v West Indies at Manchester, 3rd Test, 03/08/2000 [1506] |
| 28 | SL Campbell | West Indies v England at The Oval, 5th Test, 31/08/2000 [1509] |
| 28 | CEL Ambrose | West Indies v England at The Oval, 5th Test, 31/08/2000 [1509] |
| 27* | RDB Croft | England v West Indies at Manchester, 3rd Test, 03/08/2000 [1506] |
| 27 | AFG Griffith | West Indies v England at Lord's, 2nd Test, 29/06/2000 [1503] |
| 27 | C White | England v West Indies at Lord's, 2nd Test, 29/06/2000 [1503] |
| 27 | RR Sarwan | West Indies v England at The Oval, 5th Test, 31/08/2000 [1509] |
| 26* | RD Jacobs | West Indies v England at The Oval, 5th Test, 31/08/2000 [1509] |
| 26 | NV Knight | England v West Indies at Birmingham, 1st Test, 15/06/2000 [1500] |
| 26 | WW Hinds | West Indies v England at Manchester, 3rd Test, 03/08/2000 [1506] |
| 26 | DG Cork | England v West Indies at The Oval, 5th Test, 31/08/2000 [1509] |
| 25 | GA Hick | England v West Indies at Lord's, 2nd Test, 29/06/2000 [1503] |
| 25 | WW Hinds | West Indies v England at Manchester, 3rd Test, 03/08/2000 [1506] |
| 25 | AJ Stewart | England v West Indies at The Oval, 5th Test, 31/08/2000 [1509] |
