| 118 | HH Gibbs | South Africa v England at Durban, 6th ODI, 11/02/2005 [2225] |
| 116 | KP Pietersen | England v South Africa at Centurion, 7th ODI, 13/02/2005 [2226] |
| 115* | GC Smith | South Africa v England at East London, 5th ODI, 09/02/2005 [2224] |
| 108* | KP Pietersen | England v South Africa at Bloemfontein, 2nd ODI, 02/02/2005 [2219] |
| 105 | GC Smith | South Africa v England at Port Elizabeth, 3rd ODI, 04/02/2005 [2221] |
| 100* | KP Pietersen | England v South Africa at East London, 5th ODI, 09/02/2005 [2224] |
| 100 | HH Gibbs | South Africa v England at Cape Town, 4th ODI, 06/02/2005 [2223] |
| 80 | JM Kemp | South Africa v England at East London, 5th ODI, 09/02/2005 [2224] |
| 78 | HH Gibbs | South Africa v England at Bloemfontein, 2nd ODI, 02/02/2005 [2219] |
| 75 | KP Pietersen | England v South Africa at Cape Town, 4th ODI, 06/02/2005 [2223] |
| 71 | JH Kallis | South Africa v England at Cape Town, 4th ODI, 06/02/2005 [2223] |
| 70 | MP Vaughan | England v South Africa at East London, 5th ODI, 09/02/2005 [2224] |
| 66 | VS Solanki | England v South Africa at Port Elizabeth, 3rd ODI, 04/02/2005 [2221] |
| 63 | JH Kallis | South Africa v England at Bloemfontein, 2nd ODI, 02/02/2005 [2219] |
| 62* | AG Prince | South Africa v England at Centurion, 7th ODI, 13/02/2005 [2226] |
| 57 | JM Kemp | South Africa v England at Cape Town, 4th ODI, 06/02/2005 [2223] |
| 50 | HH Gibbs | South Africa v England at Port Elizabeth, 3rd ODI, 04/02/2005 [2221] |
| 49 | JH Kallis | South Africa v England at East London, 5th ODI, 09/02/2005 [2224] |
| 47 | GC Smith | South Africa v England at Centurion, 7th ODI, 13/02/2005 [2226] |
| 44* | MP Vaughan | England v South Africa at Johannesburg, 1st ODI, 30/01/2005 [2216] |
| 44 | MV Boucher | South Africa v England at Centurion, 7th ODI, 13/02/2005 [2226] |
| 42 | MP Vaughan | England v South Africa at Bloemfontein, 2nd ODI, 02/02/2005 [2219] |
| 41 | AF Giles | England v South Africa at Centurion, 7th ODI, 13/02/2005 [2226] |
| 40 | PD Collingwood | England v South Africa at Bloemfontein, 2nd ODI, 02/02/2005 [2219] |
| 39 | GO Jones | England v South Africa at Port Elizabeth, 3rd ODI, 04/02/2005 [2221] |
| 37 | SM Pollock | South Africa v England at Johannesburg, 1st ODI, 30/01/2005 [2216] |
| 37 | ME Trescothick | England v South Africa at Bloemfontein, 2nd ODI, 02/02/2005 [2219] |
| 37 | GO Jones | England v South Africa at East London, 5th ODI, 09/02/2005 [2224] |
| 36 | JH Kallis | South Africa v England at Centurion, 7th ODI, 13/02/2005 [2226] |
| 35 | AJ Strauss | England v South Africa at Port Elizabeth, 3rd ODI, 04/02/2005 [2221] |
| 34 | AG Prince | South Africa v England at East London, 5th ODI, 09/02/2005 [2224] |
| 33 | N Boje | South Africa v England at Johannesburg, 1st ODI, 30/01/2005 [2216] |
| 33 | ME Trescothick | England v South Africa at Port Elizabeth, 3rd ODI, 04/02/2005 [2221] |
| 33 | KP Pietersen | England v South Africa at Port Elizabeth, 3rd ODI, 04/02/2005 [2221] |
| 33 | MV Boucher | South Africa v England at Port Elizabeth, 3rd ODI, 04/02/2005 [2221] |
| 32 | JM Kemp | South Africa v England at Bloemfontein, 2nd ODI, 02/02/2005 [2219] |
| 27 | AG Prince | South Africa v England at Durban, 6th ODI, 11/02/2005 [2225] |
| 25 | GC Smith | South Africa v England at Bloemfontein, 2nd ODI, 02/02/2005 [2219] |
| 25 | Kabir Ali | England v South Africa at Centurion, 7th ODI, 13/02/2005 [2226] |
| 24 | JM Kemp | South Africa v England at Johannesburg, 1st ODI, 30/01/2005 [2216] |
| 24 | MV Boucher | South Africa v England at Durban, 6th ODI, 11/02/2005 [2225] |
| 23 | AJ Hall | South Africa v England at Centurion, 7th ODI, 13/02/2005 [2226] |
| 22* | KP Pietersen | England v South Africa at Johannesburg, 1st ODI, 30/01/2005 [2216] |
| 22 | AG Prince | South Africa v England at Johannesburg, 1st ODI, 30/01/2005 [2216] |
| 22 | PD Collingwood | England v South Africa at Port Elizabeth, 3rd ODI, 04/02/2005 [2221] |
