| 317 | CH Gayle | West Indies v South Africa at Antigua, 4th Test, 29/04/2005 [1750] |
| 213 | WW Hinds | West Indies v South Africa at Guyana, 1st Test, 31/03/2005 [1745] |
| 203* | S Chanderpaul | West Indies v South Africa at Guyana, 1st Test, 31/03/2005 [1745] |
| 196 | BC Lara | West Indies v South Africa at Trinidad, 2nd Test, 08/04/2005 [1747] |
| 178 | AB de Villiers | South Africa v West Indies at Barbados, 3rd Test, 21/04/2005 [1749] |
| 176 | BC Lara | West Indies v South Africa at Barbados, 3rd Test, 21/04/2005 [1749] |
| 148 | GC Smith | South Africa v West Indies at Trinidad, 2nd Test, 08/04/2005 [1747] |
| 147 | JH Kallis | South Africa v West Indies at Antigua, 4th Test, 29/04/2005 [1750] |
| 131 | AG Prince | South Africa v West Indies at Antigua, 4th Test, 29/04/2005 [1750] |
| 127 | RR Sarwan | West Indies v South Africa at Antigua, 4th Test, 29/04/2005 [1750] |
| 127 | S Chanderpaul | West Indies v South Africa at Antigua, 4th Test, 29/04/2005 [1750] |
| 126 | GC Smith | South Africa v West Indies at Antigua, 4th Test, 29/04/2005 [1750] |
| 114 | AB de Villiers | South Africa v West Indies at Antigua, 4th Test, 29/04/2005 [1750] |
| 109* | JH Kallis | South Africa v West Indies at Guyana, 1st Test, 31/03/2005 [1745] |
| 107* | RR Sarwan | West Indies v South Africa at Trinidad, 2nd Test, 08/04/2005 [1747] |
| 107 | DJJ Bravo | West Indies v South Africa at Antigua, 4th Test, 29/04/2005 [1750] |
| 104 | GC Smith | South Africa v West Indies at Barbados, 3rd Test, 21/04/2005 [1749] |
| 78 | JH Kallis | South Africa v West Indies at Barbados, 3rd Test, 21/04/2005 [1749] |
| 71 | HH Dippenaar | South Africa v West Indies at Barbados, 3rd Test, 21/04/2005 [1749] |
| 68 | CO Browne | West Indies v South Africa at Barbados, 3rd Test, 21/04/2005 [1749] |
| 62 | AB de Villiers | South Africa v West Indies at Trinidad, 2nd Test, 08/04/2005 [1747] |
| 56* | HH Dippenaar | South Africa v West Indies at Antigua, 4th Test, 29/04/2005 [1750] |
| 53 | S Chanderpaul | West Indies v South Africa at Barbados, 3rd Test, 21/04/2005 [1749] |
| 50* | GC Smith | South Africa v West Indies at Antigua, 4th Test, 29/04/2005 [1750] |
| 49 | HH Gibbs | South Africa v West Indies at Guyana, 1st Test, 31/03/2005 [1745] |
| 48 | RO Hinds | West Indies v South Africa at Guyana, 1st Test, 31/03/2005 [1745] |
| 45 | AG Prince | South Africa v West Indies at Trinidad, 2nd Test, 08/04/2005 [1747] |
| 41 | AB de Villiers | South Africa v West Indies at Guyana, 1st Test, 31/03/2005 [1745] |
| 41 | MV Boucher | South Africa v West Indies at Guyana, 1st Test, 31/03/2005 [1745] |
| 41 | GC Smith | South Africa v West Indies at Trinidad, 2nd Test, 08/04/2005 [1747] |
| 39 | JH Kallis | South Africa v West Indies at Trinidad, 2nd Test, 08/04/2005 [1747] |
| 35 | DJ Pagon | West Indies v South Africa at Guyana, 1st Test, 31/03/2005 [1745] |
| 35 | S Chanderpaul | West Indies v South Africa at Trinidad, 2nd Test, 08/04/2005 [1747] |
| 34 | GC Smith | South Africa v West Indies at Guyana, 1st Test, 31/03/2005 [1745] |
| 34 | N Boje | South Africa v West Indies at Guyana, 1st Test, 31/03/2005 [1745] |
| 34 | HH Gibbs | South Africa v West Indies at Trinidad, 2nd Test, 08/04/2005 [1747] |
| 33 | DJJ Bravo | West Indies v South Africa at Trinidad, 2nd Test, 08/04/2005 [1747] |
| 33 | AB de Villiers | South Africa v West Indies at Trinidad, 2nd Test, 08/04/2005 [1747] |
| 32 | WW Hinds | West Indies v South Africa at Trinidad, 2nd Test, 08/04/2005 [1747] |
| 31 | S Chanderpaul | West Indies v South Africa at Barbados, 3rd Test, 21/04/2005 [1749] |
| 28 | MV Boucher | South Africa v West Indies at Trinidad, 2nd Test, 08/04/2005 [1747] |
| 28 | MV Boucher | South Africa v West Indies at Barbados, 3rd Test, 21/04/2005 [1749] |
| 26 | CO Browne | West Indies v South Africa at Trinidad, 2nd Test, 08/04/2005 [1747] |
| 26 | DJJ Bravo | West Indies v South Africa at Barbados, 3rd Test, 21/04/2005 [1749] |
| 24 | JA Rudolph | South Africa v West Indies at Guyana, 1st Test, 31/03/2005 [1745] |
| 23 | AG Prince | South Africa v West Indies at Barbados, 3rd Test, 21/04/2005 [1749] |
| 23 | HH Gibbs | South Africa v West Indies at Antigua, 4th Test, 29/04/2005 [1750] |
| 22 | WW Hinds | West Indies v South Africa at Trinidad, 2nd Test, 08/04/2005 [1747] |
| 20* | N Boje | South Africa v West Indies at Barbados, 3rd Test, 21/04/2005 [1749] |
| 20 | AB de Villiers | South Africa v West Indies at Guyana, 1st Test, 31/03/2005 [1745] |
