| 231.81 (51/22) | Abdul Razzaq | Pakistan v England at Karachi, 3rd ODI, 15/12/2005 [2306] |
| 221.42 (31/14) | Shahid Afridi | Pakistan v England at Karachi, 3rd ODI, 15/12/2005 [2306] |
| 143.58 (56/39) | KP Pietersen | England v Pakistan at Lahore, 1st ODI, 10/12/2005 [2304] |
| 128.57 (45/35) | Inzamam-ul-Haq | Pakistan v England at Karachi, 3rd ODI, 15/12/2005 [2306] |
| 125.92 (34/27) | PD Collingwood | England v Pakistan at Lahore, 1st ODI, 10/12/2005 [2304] |
| 124.00 (31/25) | Inzamam-ul-Haq | Pakistan v England at Lahore, 2nd ODI, 12/12/2005 [2305] |
| 110.76 (72/65) | A Flintoff | England v Pakistan at Lahore, 1st ODI, 10/12/2005 [2304] |
| 107.14 (60/56) | Younis Khan | Pakistan v England at Lahore, 1st ODI, 10/12/2005 [2304] |
| 104.61 (68/65) | Mohammad Yousuf | Pakistan v England at Karachi, 3rd ODI, 15/12/2005 [2306] |
| 103.70 (28/27) | KP Pietersen | England v Pakistan at Lahore, 2nd ODI, 12/12/2005 [2305] |
| 103.07 (67/65) | Salman Butt | Pakistan v England at Lahore, 1st ODI, 10/12/2005 [2304] |
| 103.03 (34/33) | Shahid Afridi | Pakistan v England at Rawalpindi, 4th ODI, 19/12/2005 [2307] |
| 98.19 (109/111) | Kamran Akmal | Pakistan v England at Karachi, 3rd ODI, 15/12/2005 [2306] |
| 96.96 (32/33) | MJ Prior | England v Pakistan at Lahore, 2nd ODI, 12/12/2005 [2305] |
| 95.91 (94/98) | AJ Strauss | England v Pakistan at Lahore, 1st ODI, 10/12/2005 [2304] |
| 93.65 (59/63) | Mohammad Yousuf | Pakistan v England at Lahore, 1st ODI, 10/12/2005 [2304] |
| 91.89 (102/111) | Kamran Akmal | Pakistan v England at Lahore, 2nd ODI, 12/12/2005 [2305] |
| 89.58 (43/48) | Salman Butt | Pakistan v England at Lahore, 2nd ODI, 12/12/2005 [2305] |
| 88.09 (37/42) | IR Bell | England v Pakistan at Karachi, 3rd ODI, 15/12/2005 [2306] |
| 87.80 (36/41) | A Flintoff | England v Pakistan at Karachi, 3rd ODI, 15/12/2005 [2306] |
| 83.33 (50/60) | Shoaib Malik | Pakistan v England at Lahore, 1st ODI, 10/12/2005 [2304] |
| 83.33 (40/48) | A Flintoff | England v Pakistan at Rawalpindi, 4th ODI, 19/12/2005 [2307] |
| 81.81 (45/55) | MJ Prior | England v Pakistan at Lahore, 1st ODI, 10/12/2005 [2304] |
| 81.25 (39/48) | VS Solanki | England v Pakistan at Lahore, 2nd ODI, 12/12/2005 [2305] |
| 80.55 (29/36) | ID Blackwell | England v Pakistan at Rawalpindi, 4th ODI, 19/12/2005 [2307] |
| 76.47 (39/51) | Kabir Ali | England v Pakistan at Rawalpindi, 4th ODI, 19/12/2005 [2307] |
| 71.73 (33/46) | PD Collingwood | England v Pakistan at Rawalpindi, 5th ODI, 21/12/2005 [2308] |
| 71.68 (81/113) | Inzamam-ul-Haq | Pakistan v England at Rawalpindi, 4th ODI, 19/12/2005 [2307] |
| 70.00 (56/80) | LE Plunkett | England v Pakistan at Lahore, 2nd ODI, 12/12/2005 [2305] |
| 68.35 (54/79) | Mohammad Yousuf | Pakistan v England at Rawalpindi, 5th ODI, 21/12/2005 [2308] |
| 58.00 (29/50) | Salman Butt | Pakistan v England at Karachi, 3rd ODI, 15/12/2005 [2306] |
| 56.97 (49/86) | VS Solanki | England v Pakistan at Rawalpindi, 5th ODI, 21/12/2005 [2308] |
| 54.28 (57/105) | Yasir Hameed | Pakistan v England at Rawalpindi, 5th ODI, 21/12/2005 [2308] |
| 53.42 (39/73) | A Flintoff | England v Pakistan at Rawalpindi, 5th ODI, 21/12/2005 [2308] |
| 45.61 (26/57) | AJ Strauss | England v Pakistan at Rawalpindi, 5th ODI, 21/12/2005 [2308] |
| 41.17 (28/68) | Mohammad Yousuf | Pakistan v England at Lahore, 2nd ODI, 12/12/2005 [2305] |
