| 134* | GC Smith | South Africa v India at Kolkata, 4th ODI, 25/11/2005 [2299] |
| 103 | Yuvraj Singh | India v South Africa at Hyderabad, 1st ODI, 16/11/2005 [2297] |
| 91 | JH Kallis | South Africa v India at Mumbai, 5th ODI, 28/11/2005 [2300] |
| 78* | R Dravid | India v South Africa at Mumbai, 5th ODI, 28/11/2005 [2300] |
| 77* | V Sehwag | India v South Africa at Bangalore, 2nd ODI, 19/11/2005 [2298] |
| 68* | JH Kallis | South Africa v India at Hyderabad, 1st ODI, 16/11/2005 [2297] |
| 53 | Yuvraj Singh | India v South Africa at Kolkata, 4th ODI, 25/11/2005 [2299] |
| 49 | Yuvraj Singh | India v South Africa at Mumbai, 5th ODI, 28/11/2005 [2300] |
| 48* | AJ Hall | South Africa v India at Kolkata, 4th ODI, 25/11/2005 [2299] |
| 48 | GC Smith | South Africa v India at Hyderabad, 1st ODI, 16/11/2005 [2297] |
| 46* | JM Kemp | South Africa v India at Hyderabad, 1st ODI, 16/11/2005 [2297] |
| 46 | IK Pathan | India v South Africa at Hyderabad, 1st ODI, 16/11/2005 [2297] |
| 46 | AG Prince | South Africa v India at Hyderabad, 1st ODI, 16/11/2005 [2297] |
| 46 | M Kaif | India v South Africa at Kolkata, 4th ODI, 25/11/2005 [2299] |
| 38 | G Gambhir | India v South Africa at Bangalore, 2nd ODI, 19/11/2005 [2298] |
| 37* | Harbhajan Singh | India v South Africa at Hyderabad, 1st ODI, 16/11/2005 [2297] |
| 37 | IK Pathan | India v South Africa at Bangalore, 2nd ODI, 19/11/2005 [2298] |
| 35 | MV Boucher | South Africa v India at Mumbai, 5th ODI, 28/11/2005 [2300] |
| 32 | AJ Hall | South Africa v India at Bangalore, 2nd ODI, 19/11/2005 [2298] |
| 30* | SM Pollock | South Africa v India at Mumbai, 5th ODI, 28/11/2005 [2300] |
| 30 | AG Prince | South Africa v India at Bangalore, 2nd ODI, 19/11/2005 [2298] |
| 30 | V Sehwag | India v South Africa at Kolkata, 4th ODI, 25/11/2005 [2299] |
| 30 | SR Tendulkar | India v South Africa at Mumbai, 5th ODI, 28/11/2005 [2300] |
| 29 | SM Pollock | South Africa v India at Bangalore, 2nd ODI, 19/11/2005 [2298] |
| 28 | JM Kemp | South Africa v India at Bangalore, 2nd ODI, 19/11/2005 [2298] |
| 27 | V Sehwag | India v South Africa at Mumbai, 5th ODI, 28/11/2005 [2300] |
| 24 | GC Smith | South Africa v India at Mumbai, 5th ODI, 28/11/2005 [2300] |
| 21 | AB Agarkar | India v South Africa at Hyderabad, 1st ODI, 16/11/2005 [2297] |
