| 188* | G Kirsten | v United Arab Emirates at Rawalpindi, World Cup, 1995/96 [1049] |
| 161 | AC Hudson | v Netherlands at Rawalpindi, World Cup, 1995/96 [1073] |
| 146 | AB de Villiers | v West Indies at St George's, ICC World Cup, 2006/07 [2567] |
| 143 | HH Gibbs | v New Zealand at Johannesburg, World Cup, 2002/03 [1955] |
| 128* | JH Kallis | v Netherlands at Basseterre, ICC World Cup, 2006/07 [2537] |
| 101 | HH Gibbs | v Australia at Leeds, World Cup, 1999 [1481] |
| 96 | JH Kallis | v India at Hove, World Cup, 1999 [1444] |
| 92 | AB de Villiers | v Australia at Basseterre, ICC World Cup, 2006/07 [2552] |
| 91 | GC Smith | v Scotland at Basseterre, ICC World Cup, 2006/07 [2545] |
| 91 | HH Gibbs | v New Zealand at Birmingham, World Cup, 1999 [1478] |
| 90 | PN Kirsten | v New Zealand at Auckland, World Cup, 1991/92 [723] |
| 89* | GC Smith | v England at Bridgetown, ICC World Cup, 2006/07 [2574] |
| 87* | HH Gibbs | v Kenya at Potchefstroom, World Cup, 2002/03 [1947] |
| 86 | JH Kallis | v Sri Lanka at Providence, ICC World Cup, 2006/07 [2556] |
| 85 | KC Wessels | v England at Melbourne, World Cup, 1991/92 [741] |
| 84 | PN Kirsten | v India at Adelaide, World Cup, 1991/92 [745] |
| 83 | G Kirsten | v Netherlands at Rawalpindi, World Cup, 1995/96 [1073] |
| 82 | G Kirsten | v New Zealand at Birmingham, World Cup, 1999 [1478] |
| 81* | KC Wessels | v Australia at Sydney, World Cup, 1991/92 [719] |
| 81 | JH Kallis | v West Indies at St George's, ICC World Cup, 2006/07 [2567] |
| 80 | HH Dippenaar | v Canada at East London, World Cup, 2002/03 [1971] |
| 79 | AC Hudson | v England at Melbourne, World Cup, 1991/92 [741] |
| 78 | WJ Cronje | v New Zealand at Faisalabad, World Cup, 1995/96 [1054] |
| 75* | MV Boucher | v Netherlands at Basseterre, ICC World Cup, 2006/07 [2537] |
| 74 | GC Smith | v Australia at Basseterre, ICC World Cup, 2006/07 [2552] |
| 73 | HH Gibbs | v Sri Lanka at Durban, World Cup, 2002/03 [1979] |
| 72 | HH Gibbs | v Netherlands at Basseterre, ICC World Cup, 2006/07 [2537] |
| 70 | KC Wessels | v Zimbabwe at Canberra, World Cup, 1991/92 [738] |
| 69 | G Kirsten | v West Indies at Cape Town, World Cup, 2002/03 [1942] |
| 69 | DJ Cullinan | v West Indies at Karachi, World Cup, 1995/96 [1079] |
| 67 | GC Smith | v Netherlands at Basseterre, ICC World Cup, 2006/07 [2537] |
| 66* | JH Kallis | v Ireland at Providence, ICC World Cup, 2006/07 [2562] |
| 65 | DJ Cullinan | v Pakistan at Karachi, World Cup, 1995/96 [1067] |
| 63 | GC Smith | v Canada at East London, World Cup, 2002/03 [1971] |
| 62* | PN Kirsten | v Zimbabwe at Canberra, World Cup, 1991/92 [738] |
| 62 | AB de Villiers | v Scotland at Basseterre, ICC World Cup, 2006/07 [2545] |
| 61* | HH Gibbs | v West Indies at St George's, ICC World Cup, 2006/07 [2567] |
| 60 | HH Gibbs | v New Zealand at St George's, ICC World Cup, 2006/07 [2571] |
| 60 | HH Gibbs | v England at The Oval, World Cup, 1999 [1455] |
| 59 | GC Smith | v Sri Lanka at Providence, ICC World Cup, 2006/07 [2556] |
| 57 | L Klusener | v West Indies at Cape Town, World Cup, 2002/03 [1942] |
| 57 | WJ Cronje | v United Arab Emirates at Rawalpindi, World Cup, 1995/96 [1049] |
| 56* | HH Gibbs | v Bangladesh at Providence, ICC World Cup, 2006/07 [2564] |
| 56 | PN Kirsten | v West Indies at Christchurch, World Cup, 1991/92 [730] |
| 54 | JH Kallis | v Pakistan at Nottingham, World Cup, 1999 [1474] |
| 54 | AC Hudson | v West Indies at Karachi, World Cup, 1995/96 [1079] |
| 54 | AC Hudson | v Pakistan at Brisbane, World Cup, 1991/92 [735] |
| 53* | JH Kallis | v New Zealand at Birmingham, World Cup, 1999 [1478] |
| 53 | JH Kallis | v Australia at Birmingham, World Cup, 1999 [1483] |
| 53 | AC Hudson | v India at Adelaide, World Cup, 1991/92 [745] |
